. Author manuscript; available in PMC: 2014 Apr 5.

Published in final edited form as: J Proteome Res. 2013 Mar 15;12(4):1789–1796. doi: 10.1021/pr3011342

Table 4.

Frequency of autoantibody to alpha-enolase in sera from patients with liver diseases

Type of diseases	No. tested	Frequency (Patients with anti-alpha-enolase/ total patients with disease)^a
Liver fibrosis:	180	17.8% (32/180)**^b
Pre-cirrhotic stage	125	21.6% (27/125)*^b,^c
Cirrhotic stage	55	9.1% (5/55)
Liver cancer	84	14.3% (12/84)**^b

Normal human sera (NHS)	74	4.1% (3/74)

Cutoff value: Mean + 3 SD of NHS

P value relative to NHS: * p < 0.05; ** p < 0.01

P value relative to cirrhotic stage: * p < 0.05; ** p < 0.01