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. 2013 Aug 14;3(4):356–373.

Figure 3.

Figure 3

MiR-146a is upregulated by KLF8 and TGF-β in MCF-10A cells and is highly overexpressed in invasive breast cancer cells. A: Expression of the 14 miRs shown in Figure 2 was further compared between TGF-β treated and untreated MCF-10A cells to identify target miRs (Hsa-mir-146a, -219-2-3p, -508-3p, and -513a-5p) common to KLF8 and TGF-β. The expression of these 4 miRs was then examined in the indicated human breast cancer cell lines. B: MiR-146a fold difference from that in the MCF-10A cells. C: The expression of MiR-146a was compared between the cancer cells.