Table 3.
Regression coefficients for selected variables and log transformed CA-125 as a continuous variable*
| Univariate | Multivariate** | ||||||
|---|---|---|---|---|---|---|---|
| Variable | Parameter estimate |
Parameter exponentiated |
P value | Parameter estimate |
Parameter exponentiated |
P value | |
| White | -- | -- | -- | -- | |||
| Black | −0.243 | 0.784 | <0.001 | −0.208 | 0.812 | <0.001 | |
| Hispanic | −0.140 | 0.870 | <0.001 | −0.126 | 0.881 | <0.001 | |
| Asian | −0.060 | 0.942 | <0.001 | −0.084 | 0.920 | <0.001 | |
| Pacific Is/ Native Am | −0.137 | 0.872 | <0.001 | −0.120 | 0.887 | <0.001 | |
| Age 55–59 yrs | -- | -- | -- | -- | |||
| Age 60–64 yrs | 0.036 | 1.037 | <0.001 | 0.041 | 1.041 | <0.001 | |
| Age 65–69 yrs | 0.053 | 1.055 | <0.001 | 0.058 | 1.060 | <0.001 | |
| Age 70–74 yrs | 0.070 | 1.073 | <0.001 | 0.073 | 1.075 | <0.001 | |
| High School graduate | -- | -- | -- | -- | -- | -- | |
| <12 years | −0.035 | 0.965 | 0.005 | −0.002 | 0.998 | 0.878 | |
| Post High School | 0.009 | 1.009 | 0.137 | −0.007 | 0.993 | 0.232 | |
| Age at Menopause 50–54 yrs |
-- | -- | -- | -- | -- | -- | |
| <40 yrs | −0.114 | 0.892 | <0.001 | −0.017 | 0.984 | 0.150 | |
| 40–44 yrs | −0.058 | 0.944 | <0.001 | −0.009 | 0.991 | 0.378 | |
| 45–49 yrs | −0.021 | 0.979 | 0.005 | −0.004 | 0.996 | 0.570 | |
| 55+ yrs | 0.046 | 1.047 | <0.001 | 0.043 | 1.044 | <0.001 | |
| History of Breast Cancer | 0.046 | 1.048 | 0.002 | 0.046 | 1.047 | 0.002 | |
| Family History of Ovarian Cancer | −0.010 | 0.990 | 0.473 | −0.011 | 0.989 | 0.426 | |
| Family History of Breast Cancer | −0.011 | 0.989 | 0.168 | −0.015 | 0.986 | 0.066 | |
| History of Ovarian Tumors/Cysts | −0.022 | 0.978 | 0.021 | 0.007 | 0.993 | 0.473 | |
| History of Uterine Fibroids | −0.029 | 0.971 | <0.001 | 0.009 | 1.009 | 0.250 | |
| History of Endometriosis | −0.028 | 0.972 | 0.018 | −0.004 | 0.996 | 0.721 | |
| Partial Oophorectomy | −0.082 | 0.921 | <0.001 | −0.024 | 0.976 | 0.265 | |
| Hysterectomy | −0.112 | 0.894 | <0.001 | −0.100 | 0.905 | <0.001 | |
| No Hormone Therapy | -- | -- | -- | -- | -- | -- | |
| Former Hormone Therapy | 0.027 | 1.028 | <0.001 | 0.031 | 1.031 | <0.001 | |
| Current Hormone Therapy | 0.0233 | 1.024 | <0.001 | 0.040 | 1.041 | <0.001 | |
| Never Smoker | -- | -- | -- | -- | |||
| Former Smoker | 0.015 | 1.015 | 0.016 | 0.014 | 1.014 | 0.017 | |
| Current Smoker | −0.111 | 0.895 | <0.001 | −0.094 | 0.910 | <0.001 | |
| Normal Weight*** | -- | -- | -- | -- | |||
| Overweight | −0.010 | 0.990 | 0.108 | −0.004 | 0.996 | 0.493 | |
| Obese | −0.050 | 0.951 | <0.001 | −0.030 | 0.970 | <0.001 | |
*
statistics estimated using linear regression
**
adjusted for all other variables on the table
***
Normal defined as BMI <25 kg/m2; Overweight as BMI =25–29 kg/m2; Obese as BMI ≥30 kg/m2