Group 1 |
Non-arthritic control/IFA (intraplantar injection of 0.1 ml of IFA) |
Group 2 |
Arthritic control/CFA (intraplantar injection of 0.1 ml CFA) |
Groups 3–6 |
TWE (30, 100, 300 and 1000 mg kg−1
p.o. respectively) daily |
Groups 7–10 |
TAE (30, 100, 300 and 1000 mg kg−1
p.o. respectively) daily |
Groups 11–14 |
TPEE (30–1000 mg kg−1
p.o. respectively) daily, starting from day 10 |
Groups 15–17 |
Dexamethasone (0.1, 0.3 and 1.0 mg kg−1
i.p. respectively) every other day. |
Groups 18–20 |
Diclofenac (10, 30 and 100 mg kg−1
i.p. respectively) every other day. |
Groups 21–23 |
Methotrexate (1.0, 0.3 and 1.0 mg kg−1
i.p. respectively) every four days. |