Table 1.

Effect of 5 days of repeated oral administration of 200 mg/kg of HU_c, HU_e, HU_b and HU_m on the fasting blood glucose concentrations in alloxan-induced hyperglycaemic rats

Groups	fasting blood glucose (FBG) (mg/dl) on		% FBG inhibition
	day 1	day 6
I	76.00 ± 3.21	77.60 ± 0.93	2.66 ± 3.96
II	230.20 ± 5.38c	255.00 ± 8.39c, a	10.69 ± 1.42a+
III	229.40 ± 5.57c	114.40 ± 2.79e	−50.12 ± 0.56f
IV	231.40 ± 8.47c	218.20 ± 9.60d	−5.79 ± 1.34d
V	224.00 ± 5.50c	203.80 ± 6.80d	−9.09 ± 1.03d
VI	221.80 ± 6.71c	116.20 ± 5.67 e	−48.53 ± 1.77f
VII	231.40 ± 7.13c	196.20 ± 9.45d	−15.37 ± 1.96d

^c represents a significant increase at p<0.001 when compared to basal value at day 0 while ^{d, e} and ^f represent significant decreases at p<0.05, p<0.01 and p<0.001, respectively, when compared to Group II values on day 6 and ^a+ represents a significant increase at p<0.05 when compared to Group I and Group II values on day 0.

I = normoglycaemic rats + 10 ml/kg of 5% Tween 20 in distilled water; II = alloxan hyperglycaemic rats + 10 ml/kg of 5% Tween 20 in distilled water; III= alloxan hyperglycaemic rats + 1 mg/kg glibenclamide in 5% Tween 20 in distilled water

IV = hyperglycaemic rats + 200 mg/kg of HU_c in 5% Tween 20 in distilled water; V = hyperglycaemic rats + 200 mg/kg of HU_e in 5% Tween 20 in distilled water ; VI = hyperglycaemic rats + 200 mg/kg of HU_b in 5% Tween 20 in distilled water

VII = hyperglycaemic rats + 200 mg/kg of HU_m in 5% Tween 20 in distilled water