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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Circ Res. 2013 May 21;113(3):288–300. doi: 10.1161/CIRCRESAHA.113.300929

Figure 3.

Figure 3

Transplantation of ADSCs with PHD2 silencing reduces cardiomyocyte loss and fibrosis. A: Representative images (A1) and quantification (A2) of TUNEL+ cardiomyocytes in infarct border zone at 48 hours post-MI. TUNEL+ nuclei are stained green, tropomyosin is red and DAPI is blue. B: Representative images (B1) and quantification (B2) of fibrotic area in infarct border zone by Masson's trichrome staining at 4 weeks post-MI. For A and B, scale bar = 50 μm. C: Representative images (C1) and quantification (C2) of capillary density in infarct border zone at 4 weeks post-MI analyzed by CD31 staining. Scale bar = 30 μm. D: Representative contour plots (D1) and quantification (D2) of infiltrating monocyte population (Ly6Chigh/CD11b+) in cells isolated from infracted hearts at 48 hours post-MI analyzed by FACS analysis. N=6. * p<0.05 vs. MI+PBS; # p<0.05 vs. MI+GFP-ADSCs.