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A-factor production by the wild-type (wt) S. griseus strain and ΔarpA, MK2, and ΔadpA mutants. (A) Growth was monitored by measuring the wet weight of mycelium grown in YMPD liquid medium. (B) The A-factor concentration was measured by the streptomycin cosynthesis method, as described previously (4). The values are the averages of results for two independent samples.
