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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Stat Med. 2012 Sep 27;32(7):1164–1190. doi: 10.1002/sim.5628

Figure 2.

Figure 2

Quantile-quantile plots of the empirical values of ΛR obtained under the null hypothesis of no interaction and expected values under a central chi-squared distribution with one degree of freedom under various parametric configurations. The 3 rows correspond to data generated with correlation between the risk factors as ρ = 0 (uncorrelated), 0.50, and 0.80. The columns correspond to null simulations with different magnitudes of the main effects.