Table 1. Relative specific infectivities of MHV-ExoN+ and ExoN− viruses following treatment with RBV or 5-FU.

Virus	RBV(µM)	Relative Specific Infectivity	Fold Decrease	5-FU (µM)	Relative Specific Infectivity	Fold Decrease
MHV-ExoN+	0	1		0	1
	5	1.2±0.1	0.84±0.06	100	0.33±0.05	3.4±0.5
	10	1.9±0.2	0.56±0.05	200	0.24±0.03	4.5±0.4
MHV-ExoN−	0	1		0	1
	5	0.19±0.04	6.0±0.7***	100	0.10±0.03	13.6±2.9**
	10	0.26±0.11	9.1±3.0*	200	0.012±0.004	128±29**

Relative specific infectivity values were calculated using the data shown in Figures 1C and 2C and represent the change in virus titer divided by the change in virus genome for each sample. All values are shown relative to untreated virus. The mean value and standard error for each sample is shown (Student's t test, n = 4, *P<0.05, **P<0.01, ***P<0.0001).