Skip to main content
. 2013 Aug 15;9(8):e1003699. doi: 10.1371/journal.pgen.1003699

Figure 6. TFIIIC regulates dendritic growth.

Figure 6

(A) Representative images of cortical neurons transfected with a GFP-expressing vector alone or in combination with either control or Gtf3c5 siRNA. Neurons were cultured for 2 days in basal conditions or in presence of 50 mM KCl, followed by GFP immunostaining. Shown are the enhanced profiles of neurons after reconstruction with a trainable segmentation tool. (B) Sholl profiles of neurons maintained in basal conditions (above) or exposed to KCl (below). For each distance point, the average number of intersections and s.e.m. are shown. At least 25 cells per condition were analysed (*, P<0.05; **, P<0.01; ***, P<0.001, two-way ANOVA). (C) Total length of the dendritic processes of the cells analysed in (B). Average and s.e.m. are shown (*, P<0.05; **, P<0.01, two-way ANOVA).