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. 2013 Aug 15;8(8):e71846. doi: 10.1371/journal.pone.0071846

Table 4. LPC16∶0 and LPC20∶4 negatively correlate with CVD risk factors whereas SM38∶2 positively correlates with CVD risk factors.

Lipid specie LPC16∶0 LPC20∶4 SM38∶2
Correlation P q-value Correlation P q-value Correlation P q-value
Imtcca0 −0.13 0.010 0.007 0.03 0.591 0.218 0.09 0.112 0.062
HbA1c −0.12 0.012 0.009 0.09 0.074 0.043 0.05 0.385 0.163
BMI −0.14 0.004 0.003 −0.19 2.0E-04 2.2E-04 0.04 0.438 0.180
SBP 0.06 0.244 0.114 −0.11 0.039 0.025 0.02 0.710 0.247
LDL 0.07 0.154 0.081 0.05 0.356 0.153 0.36 7.4E-11 2.6E-09
HDL 0.12 0.014 0.011 0.18 5.5E-04 5.8E-04 0.06 0.262 0.121

Partial correlations were performed between LPC16∶0, LPC20∶4, or SM38∶2 after log transformation and current known laboratory predictors for cardiovascular disease, adjusting for age and sex. BMI, body mass index; HbA1c, haemoglobin A1c; HDL, high-density lipoprotein cholesterol; Imtcca0, intima-media thickness of the common carotid artery at baseline; LDL, low-density lipoprotein cholesterol; LPC, lysophosphatidylcholine; SBP, systolic blood pressure; SM, sphingomyelin.