Table 4. Characteristics of studies included in the meta-analysis.

Study	Ethnicity	Control					Longevity					P b
		Agea	VV	VI	II	MAF	Agea	VV	VI	II	MAF
Barzilai (2003) [16]	Ashkenazi Jews	71.3	11	75	43	0.38	98.2	37	72	47	0.47	0.003
Kolovou (2013) [19]	Europeans	60	9	45	43	0.32	93	23	97	75	0.37	0.584
Cellini (2005) [21]	Europeans	69.2	19	95	75	0.35	99.6	15	77	83	0.31	0.329
Vergani (2006) [22]	Europeans	31	7	61	32	0.38	89	17	44	39	0.38	0.022
Novelli-1c (2008) [20]	White Americans	27.4	40	165	143	0.35	101.7	33	146	182	0.29	0.043
Novelli-2c (2008) [20]	White Americans	27.4	40	165	143	0.35	95.9	41	149	171	0.32	0.214
Sun (2007) [24]	East Asians	67	6	31	16	0.41	97	23	92	76	0.36	0.385
Zhang (2011) [23]	East Asians	62.8	107	146	48	0.60	100.5	45	152	79	0.44	<0.001
This study	East Asians	41.4	110	270	135	0.48	92.5	84	242	180	0.41	0.003

^a mean age (years); ^b P value within each cohort estimated based on additive model (df=2); ^c The study was divided into two comparisons because it was consisted of 2 subgroup of longevity MAF: minor allele frequency; genotype (II, VI and VV) number, mean of age and MAF are taken from corresponding studies