Table 3. In comparison to placebo, B. infantis 35624 feeding reduces plasma CRP, TNF-α and IL-6 levels, expressed as % change from baseline, in inflammatory disorder patients.
| Disease Indication | Treatment | % Change in the level of CRP |
% Change in the level of TNF-α | % Change in the level of IL-6 |
|---|---|---|---|---|
|
Psoriasis |
B. infantis |
-34.0 (-64.0, -7.25) |
-15.5 (-20.0, 3.50) |
-3.0 (-13.0, 16.0) |
| Placebo |
2.0 (-31.75,154.8) |
0.0 (-22.0, 15.0) |
-5.0 (-20.5, 11.25) |
|
|
Chronic Fatigue Syndrome |
B. infantis |
-12.0 (-55.0, 15.75) |
-6.0 (-13.0, 4.0) |
-14.0 (-26.5, -5.0) |
| Placebo |
34.0 (-15.0, 211.3) |
3.0 (-6.0, 17.0) |
4.0 (-10.5, 25.5) |
|
| Ulcerative Colitis |
B. infantis |
-38.0 (-79.0, 178.0) |
-5.0 (-9.50, 8.50) |
-5.0 (-33.0, 36.5) |
| Placebo | 261.0 (19.0, 395.5) | 5.0 (-11.0, 20.0) | 27.0 (-3.5, 137.0) |