Figure 4. Inhibition of cell signaling in PC3 cells following treatment with CTA095.

Cells were grown in 10 mm plate to 50% confluence and treated with CTA095. Cells were harvested after 24 h. pEtk, Etk, pSrc, Src, pStat3, Stat3, pAkt and Akt levels were measured using the corresponding antibodies by Western blot. One of three similar experiments depicted.