Table 1. Descriptive statistics of the three independent study samples.
| Sample-A Cases1N = 604 | Sample-B Cases2N = 535 | Healthy ControlsN = 535 | Nominal p value3 | |
| Age (yrs) | 49.2±13.1 | 41.8±10.9 | 33.1±10.2 | <0.001 |
| Antipsychotics dose (CPZ equivalents, mg) | 491.5±527.1 | 424.5±433.5 | – | |
| PANSS | ||||
| Positive subscale | 9.91±3.79 | 11.8±5.74 | – | |
| Negative subscale | 12.3±5.27 | 12.9±6.31 | – | |
| General psychopathology subscale | 21.3±5.27 | 24.1±8.77 | – | |
| Tardive dyskinesia percentage | 25.5% | – | – | |
| Drug-induced Parkinsonism percentage | 32.1% | – | – | |
| Education | <0.001 | |||
| Less than Primary4 | – | 0.39% | 0.00% | |
| Primary | – | 19.3% | 1.33% | |
| Secondary | – | 49.4% | 25.3% | |
| Junior College or polytechnic | – | 19.3% | 27.6% | |
| University or higher | – | 11.6% | 45.7% | |
| Living Apartment | – | <0.001 | ||
| 1-room | – | 8.32% | 0.23% | |
| 2/3-room | – | 31.3% | 15.2% | |
| 4/5-room | – | 41.0% | 64.8% | |
| Private house | – | 3.46% | 12.1% | |
| Others4 | – | 15.5% | 7.69% | |
| Occupation | <0.001 | |||
| Unemployed | – | 55.7% | 7.94% | |
| Manual labor | – | 4.47% | 0.95% | |
| Admin and sales | – | 3.89% | 8.32% | |
| Professional management | – | 0.78% | 14.5% | |
| Others4 | – | 35.2% | 68.2% |
1
Education, living apartment and occupation information were not collected for sample-A.
2
AIMS and SAS assessments were only performed on patients in Sample-A. Therefore, tardive dyskinesia and drug-induced Parkinsonism status were not available for Sample-B.
3
Nominal p values were computed based on Sample-B cases and healthy controls.
4
The group was used as reference group in regression analysis.