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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Pediatr. 2013 May 8;163(3):652–657.e2. doi: 10.1016/j.jpeds.2013.03.081

Table 3.

Dose-dependent relationship between fetal inflammatory response and NDI/death

NDI or death Mortality NDI
N (%) Adjusted RR (95%CI)* N (%) Adjusted RR (95%CI)* N (%) Adjusted RR (95%CI)*
No histologic chorioamnionitis 70 (35) Referent 45 (23) Referent 25 (16) Referent
Histologic chorioamnionitis, no funisitis 22 (58) 1.50 (1.04 – 2.14) 16 (42) 1.62 (1.00 – 2.21) 6 (27) 1.88 (0.89 – 3.96)
Histologic chorioamnionitis, stage 1 or 2 funisitis without chorionic vasculitis 6 (23) 0.81 (0.44 – 1.50) 5 (19) 1.12 (0.52 – 2.39) 1 (5) 0.59 (0.14 – 2.51)
Histologic chorioamnionitis, stage 1 or 2 funisitis with grade 1 chorionic vasculitis 28 (47) 1.22 (0.88 – 1.70) 21 (36) 1.39 (0.89 – 2.15) 7 (18) 1.19 (0.59 – 2.40)
Histologic chorioamnionitis, subacute necrotizing funisitis or grade 2 chorionic vasculitis 15 (60) 1.94 (1.27 – 2.96) 10 (40) 2.01 (1.12 – 3.59) 5 (33) 2.52 (1.11 – 5.72)
*

Adjusted for 100-g increment in BW, singleton birth, and preeclampsia.