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Correlations of pMHC stability with immunogenicity and CD8+ T-cell co-existence. (A) The magnitude of the T4 MVP-specific response versus the kinetic stability of the variant peptides. (B) The ratio of the T5 to T4 MVP population size versus the ratio of T5 to T4 MVP-kinetic stability. All the data points are shown in Table 1 and Fig. 4. Curves were fitted by GraphPad Prism 4 software using non-linear regression and one phase exponential association.
