Change in MSIS-29-PHYS score over time
Datapoints show mean MSIS-29-PHYS score; vertical lines show 95% CI. MSIS-29-PHYS=29-item multiple sclerosis impact scale, physical impact subscale. n=number of patients with total scores calculated at each visit. *If deterioration was noted at 36 months, a final follow-up visit was done at 42 months to confirm progression; if a patient went on to have an assessment at 42 months, data from this visit were used; if not, data from the assessment at 36 months were used.