Table 1.
Compound | % RT Activity |
---|---|
DK | 95 +/- 2 |
DL | 100 +/- 10 |
DM | 94 +/- 3 |
DP | 100 +/- 1 |
DMSO | 94 +/- 5 |
LAV | 100 +/- 0 |
Mock | 0 +/- 0 |
Inhibition of reverse transcriptase (RT) enzyme activity was determined by performing RT assays in the presence of the compounds DK, DM and DP at a concentration of 1.5 µg/mL, and DL at a concentration of 0.5 µg/mL. Controls for DMSO concentration present in compound wells (DMSO) and absence of compound (LAV) were included. A control with no virus present (mock) was also performed.