Table 3.

Effect of psychotherapy on hemodynamic responses—voxel-wise whole brain analysis.

Region		Coordinates			Peak t value	Cluster size	FWE value	Effect
		x	y	z
All emotions ([“anger”+ “disgust” + “joy” + “neutral”] − “control”)
No	Region
Anger (“anger” − “control”)
Left	Parahippocampal gyrus	−25	41	−16	5.560	11	0.998	p2 > p1
Rightt	Parahippocampal gyrus	22	26	−16	6.130	11	0.998	p2 > p1
Left	Putamen	−26	−11	5	5.322	11	0.998	p2 < p1
joy (“joy” − “control”)
Left	Inferior temporal gyrus	−53	−1	−32	6.173	12	0.960	p2 > p1

We implemented a voxel-wise whole brain analysis to identify brain regions with significant changes of hemodynamic modulation for the contrasts all emotions ([“anger”+ “disgust” + “joy” + “neutral”] − “control”), anger (“anger” − “control”), and joy (“joy” − “control”). (Abbreviations: x, y, and z refer to the Talairach coordinates of the center of mass of the regions; peak t value refers to the t value of the peak voxel in the cluster; cluster size refers to the number of voxels which survived threshold masking at p_{[uncorrected]} ≤ 0.001; FWE value describes the probability, that a cluster of the given size would appear as a false positive result in a contrast of the given smoothness; effect refers to an increase (p2 > p1) or a decrease (p2 < p1) of hemodynamic responses after psychotherapy.)