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. 2011 Jan 18;19(2):95–105. doi: 10.1016/j.jsps.2011.01.002

Table 5.

Tensile strength (MNm−2), brittle fracture index (BFI) and friability (%) at relative density, D, of 0.90 for chloroquine phosphate tablets (mean ± SD, n = 4).

Binder Binder concentration (% w/w) T (MNm−2) BFI Friability (%)
0.00 0.525 ± 0.021 0.466 ± 0.009 3.25 ± 0.13



Bitter 2.50 0.804 ± 0.010 0.370 ± 0.029 0.78 ± 0.01
5.00 1.059 ± 0.009 0.215 ± 0.022 0.63 ± 0.02
7.50 1.150 ± 0.018 0.200 ± 0.017 0.62 ± 0.01
10.00 1.272 ± 0.020 0.147 ± 0.010 0.55 ± 0.01



Chinese 2.50 0.942 ± 0.011 0.136 ± 0.011 0.70 ± 0.01
5.00 1.171 ± 0.016 0.123 ± 0.009 0.64 ± 0.02
7.50 1.248 ± 0.010 0.106 ± 0.004 0.60 ± 0.01
10.00 1.287 ± 0.013 0.100 ± 0.010 0.55 ± 0.02



Water 2.50 0.656 ± 0.007 0.615 ± 0.010 3.75 ± 0.13
5.00 0.801 ± 0.010 0.453 ± 0.021 3.00 ± 0.02
7.50 1.045 ± 0.012 0.406 ± 0.019 2.63 ± 0.02
10.00 1.155 ± 0.019 0.367 ± 0.013 2.25 ± 0.03



White 2.50 0.601 ± 0.016 0.437 ± 0.024 2.40 ± 0.05
5.00 1.057 ± 0.012 0.383 ± 0.009 2.10 ± 0.03
7.50 1.207 ± 0.009 0.314 ± 0.029 1.70 ± 0.03
10.00 1.249 ± 0.017 0.313 ± 0.023 0.96 ± 0.02



Corn 2.50 0.929 ± 0.010 0.399 ± 0.012 2.00 ± 0.10
5.00 1.016 ± 0.018 0.363 ± 0.016 1.52 ± 0.03
7.50 1.131 ± 0.014 0.349 ± 0.003 1.45 ± 0.03
10.00 1.155 ± 0.011 0.307 ± 0.002 0.90 ± 0.02