Table 2.

Permeation of ascorbic acid through freshly excised goat cornea (paired) from solutions made isotonic with NaCl or Dextrose. Values are mean ± SEM of 3 corneas in each group.

Concentration (w/v)	Tonicity adjusting substances	Amount permeated (mg) (120 min)	Permeation (%) (120 min)	Corneal hydration (%)
0.50%	NaCl∗	0.025 ± 0.004	0.5	75.04 ± 2.8
	Dextrose	0.035 ± 0.01†	0.98	77.22 ± 2.1
1.0%	NaCl∗	0.075 ± 0.01	0.75	78.54 ± 0.621
	Dextrose	0.048 ± 0.006†	0.35	78.15 ± 0.31

^†Statistically significant (P < 0.05) compared with solution containing NaCl as determined by paired t-test.