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. 2011 Mar 31;19(3):165–170. doi: 10.1016/j.jsps.2011.03.007

Table 5.

Permeation of ascorbic acid through freshly excised goat cornea (paired) from solution containing MAG (Na+–K+ ATPase inhibitor, 50 μmol) or Ouabain (Na+–K+ ATPase inhibitor, 1 mmol). Values are mean ± SEM of 3 corneas in each group.

Concentration (w/v) Amount permeated (mg) (120 min) Permeation (%) (120 min) Corneal hydration (%)
1.0% Control 0.087 ± 0.006 0.87 78.65 ± 1.46
MAG 0.047 ± 0.003 0.47 77.15 ± 1.52
1.0% Control 0.11 ± 0.017 1.1 79.64 ± 1.34
Quabain 0.066 ± 0.003 0.66 75.69 ± 1.67

Statistically significant (P < 0.05) compared with solution without MAG or without Ouabain (control) as determined by paired t-test.