Table 3.
Univariate analysis for predicting adrenal metastasis in patients with known primary cancer and categorisation by primary cancer type
| Parameters | Findings | All patients with known primary tumour (n=229) | Patients with gastrointestinal cancer (n=103) | Patients with lung cancer (n=31) | Patients with liver cancer (n=25) | ||||
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | ||
| Age (years) | 0.96 (0.94, 0.98) | 0.024 | 0.95 (0.94, 1.00) | 0.142 | 0.91 (0.86, 0.99) | 0.028 | 1.05 (0.97, 1.18) | 0.176 | |
| Left adrenal | Nodule or mass | 2.31 (1.34, 3.95) | 0.042 | 2.15 (0.88, 5.30) | 0.093 | 2.04 (0.51, 8.24) | 0.317 | 1.68 (0.31, 9.01) | 0.553 |
| Right adrenal | Nodule or mass | 2.38 (1.29, 4.21) | 0.038 | 1.35 (0.46, 3.58) | 0.631 | 1.45 (0.35, 7.29) | 0.638 | 9.07 (0.86, 97.53) | 0.068 |
| Unenhanced | ≤10 HU | 3.25 (1.54, 9.26) | <0.001 | 2.99 (1.34, 9.06) | <0.001 | 12.57 (1.42, 86.51) | 0.031 | NA | |
| Attenuation | >10 HU | 414.5 (34.1, 3712.1) | <0.001 | 321.5 (12.1, 2095.1) | <0.001 | 6.54 (1.01, 78.42) | 0.044 | NA | |
| SUVmax ratio | ≤2.5 | 15.4 (6.3, 38.2) | <0.001 | 39.4 (7.3, 210.8) | <0.001 | 17.5 (1.4, 171.5) | 0.015 | 8.30 (0.76, 93.22) | 0.085 |
| >2.5 | 509.8 (58.2, 4215.4) | <0.001 | 321.0 (27.2, 3712.8) | <0.001 | NA | NA | |||
| Metastasis in other parts | Yes | 5.35 (2.05, 8.99) | <0.001 | 5.05 (2.09, 12.51) | <0.001 | 14.2 (1.6, 129.2) | 0.019 | 3.68 (0.88, 23.23) | 0.141 |
| Primary | Lung cancer | 2.52 (1.32, 4.93) | 0.004 | ||||||
| Gastrointestinal cancer | 0.68 (0.32, 1.43) | 0.180 | |||||||
| Liver cancer | 0.71 (0.32, 1.81) | 0.006 | |||||||
| Other | — | ||||||||
NA, not applicable; OR, odds ratio; SUVmax, maximum standardised uptake value; 95% CI, confidence interval. Reference groups indicate that the corresponding variable had a significant influence on adrenal metastasis. NA indicates that the odds ratio was not performed owing to small or zero count.