Table 1.

Effect of different concentrations of SDH (10⁻¹⁵, 10⁻¹², 10⁻⁹ and 10⁻⁶ mg/ml) on the time-course of nitrite-induced oxidation of hemoglobin.

Silibinin concentrations (mg/ml)	% Formation of MetHb	% Inhibition of MetHb	Time to form 50% MetHb (t1/2) (min)
Control	100	0	25
Silibinin 10−15	35.7	64.3	70
Silibinin 10−12	28	72	89.4
Silibinin 10−9	20.5	79.5	121.9
Silibinin 10−6	17.6	82.4	150

Values represent mean of three experiments.