Table 1.
Level of Evidence | Qualifying Studies |
---|---|
I | High-quality, multicenter or single-center, randomized controlled trial with adequate power; or systematic review of these studies |
II | Lesser-quality, randomized controlled trial; prospective cohort study; or systematic review of these studies |
III | Retrospective comparative study, case–control study, or systematic review of these studies |
IV | Case series |
V | Expert opinion; case report or clinical example; or evidence based on physiology, bench research, or “first principles” |