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The enzymatic activity and localization of mammalian sirtuins
| Enzymatic activity
|
Localization | ||
|---|---|---|---|
| Deacetylase | ADP-ribosyltransferase | ||
| Sirt1 | ✓ | Nucleus, cytoplasm | |
| Sirt2 | ✓ | Cytoplasm, nucleus | |
| Sirt3 | ✓ | Mitochondria | |
| Sirt4 | ✓ | Mitochondria | |
| Sirt5 | ✓ | Mitochondria | |
| Sirt6 | ✓ | ✓ | Nucleus |
| Sirt7 | ✓ | Nucleolus | |
