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. 2013 Aug 16;8(8):e72197. doi: 10.1371/journal.pone.0072197

Table 3. Stratification analysis for associations between BCL2 rs1564483 (c*1204G>A) genotypes and risk of lung cancer.

Variables GG GA AA GA+AA P trend P interaction
OR OR(95%CI) P OR(95%CI) P OR(95%CI) P
Age 0.008
≤60 1.00 0.91(0.68–1.21) 0.519 0.77(0.50–1.17) 0.214 0.88(0.67–1.15) 0.343 0.220
>60 1.00 0.66(0.49–0.88) 0.005 0.71(0.46–1.09) 0.116 0.67(0.51–0.88) 0.004 0.017
Smoking status 0.659
Never-smokers 1.00 0.72(0.48–1.10) 0.126 0.75(0.40–1.41) 0.375 0.73(0.49–1.08) 0.117 0.188
Smokers 1.00 0.83(0.67–1.04) 0.109 0.75(0.54–1.03) 0.076 0.81(0.66–1.00) 0.049 0.043
Pack-years smoked 0.913
≤26 1.00 0.79(0.54–1.15) 0.223 0.90(0.53–1.53) 0.704 0.82(0.57–1.16) 0.263 0.452
>26 1.00 0.81(0.61–1.08) 0.152 0.67(0.44–1.02) 0.062 0.78(0.59–1.02) 0.073 0.044
Family history of cancer 0.124
No 1.00 0.74(0.60–0.92) 0.006 0.71(0.52–0.97) 0.030 0.73(0.60–0.90) 0.003 0.005
Yes 1.00 1.34(0.62–2.90) 0.453 0.96(0.29–3.27) 0.959 1.26(0.61–2.61) 0.534 0.743

Note: ORs and P values were obtained from logistic regression models with adjustment for age, smoking status, pack-year smoked, and family history of cancer.