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. 2013 Aug 16;8(8):e72197. doi: 10.1371/journal.pone.0072197

Table 4. Patient characteristics and clinical features.

Variables Patients, n(%)(N = 242) Deaths(n = 185) MST (month) Log-rank P HR(95%CI)*
Age
≤65 113(46.7) 83 16.5 0.034 Reference
>65 129(53.3) 102 11.7 1.37(1.02–1.83)
Smoking
Never 17(7.0) 13 11.3 Reference
Former 142(58.7) 109 13.5 0.802 0.93(0.53–1.66)
Current 83(34.3) 63 13.4 0.85(0.47–1.56)
Histology
Adenocarcinoma 81(33.5) 59 15.0 Reference
SCC 75(31.0) 55 15.8 0.060 0.87(0.60–1.26)
Others 86(35.5) 71 10.8 1.31(0.93–1.85)
Stage
IIIA 63(26.0) 42 18.9 Reference
IIIB 61(25.2) 44 14.7 0.001 1.25(0.82–1.91)
IV 118(48.8) 99 10.7 1.87(1.30–2.69)
Surgery
No 171(70.7) 128 12.7 0.088 Reference
Yes 71(29.3) 57 15.0 0.76(0.56–1.04)
Chemotherapy
No 59(24.4) 44 11.0 0.249 Reference
Yes 183(75.6) 141 13.7 0.82(0.58–1.15)
Radiotherapy
No 132(54.5) 98 12.5 0.308 Reference
Yes 110(45.5) 87 15.0 0.86(0.64–1.15)

Abbreviations: MST, median survival time; SCC, Squamous cell carcinoma; HR, hazard ratio.

*

Data were calculated by univariate cox regression analysis.

Others include large cell, bronchioalveolar, mixed cell, undifferentiated and pathologic not otherwise specified carcinomas.