Table 4. Patient characteristics and clinical features.
Variables | Patients, n(%)(N = 242) | Deaths(n = 185) | MST (month) | Log-rank P | HR(95%CI)* |
Age | |||||
≤65 | 113(46.7) | 83 | 16.5 | 0.034 | Reference |
>65 | 129(53.3) | 102 | 11.7 | 1.37(1.02–1.83) | |
Smoking | |||||
Never | 17(7.0) | 13 | 11.3 | Reference | |
Former | 142(58.7) | 109 | 13.5 | 0.802 | 0.93(0.53–1.66) |
Current | 83(34.3) | 63 | 13.4 | 0.85(0.47–1.56) | |
Histology | |||||
Adenocarcinoma | 81(33.5) | 59 | 15.0 | Reference | |
SCC | 75(31.0) | 55 | 15.8 | 0.060 | 0.87(0.60–1.26) |
Others† | 86(35.5) | 71 | 10.8 | 1.31(0.93–1.85) | |
Stage | |||||
IIIA | 63(26.0) | 42 | 18.9 | Reference | |
IIIB | 61(25.2) | 44 | 14.7 | 0.001 | 1.25(0.82–1.91) |
IV | 118(48.8) | 99 | 10.7 | 1.87(1.30–2.69) | |
Surgery | |||||
No | 171(70.7) | 128 | 12.7 | 0.088 | Reference |
Yes | 71(29.3) | 57 | 15.0 | 0.76(0.56–1.04) | |
Chemotherapy | |||||
No | 59(24.4) | 44 | 11.0 | 0.249 | Reference |
Yes | 183(75.6) | 141 | 13.7 | 0.82(0.58–1.15) | |
Radiotherapy | |||||
No | 132(54.5) | 98 | 12.5 | 0.308 | Reference |
Yes | 110(45.5) | 87 | 15.0 | 0.86(0.64–1.15) |
Abbreviations: MST, median survival time; SCC, Squamous cell carcinoma; HR, hazard ratio.
Data were calculated by univariate cox regression analysis.
Others include large cell, bronchioalveolar, mixed cell, undifferentiated and pathologic not otherwise specified carcinomas.