Table 6. Stratification analysis for associations between BCL2 rs1564483 (c^*1204G>A) genotypes and overall survival of male advance NSCLC patients.

	GG		GA+AA
Variables	np/nd	MST	np/nd	MST	Log- rank P	HR(95%CI)*	P *	P interaction *
Age								0.690
≤65	43/34	12.0	70/49	17.6	0.187	0.68(0.42–1.09)	0.110
>65	59/49	11.0	70/53	12.7	0.166	0.67(0.44–1.01)	0.057
Smoking								0.900
Never-smokers	6/5	7.4	11/8	11.3	0.952	0.07(0.01–1.30)	0.074
Smokers	96/78	11.7	129/94	15.3	0.037	0.68(0.50–0.93)	0.016
Histology								0.549
Adenocarcinoma	31/24	11.5	50/35	17.4	0.514	0.73(0.39–1.34)	0.306
SCC	34/27	15.8	41/28	17.6	0.146	0.74(0.41–1.35)	0.332
Others†	37/32	9.7	49/39	12.6	0.138	0.68(0.41–1.10)	0.117
Stage								0.340
IIIA	25/18	13.7	38/24	20.7	0.031	0.49(0.25–0.96)	0.037
IIIB	29/24	15.8	32/20	12.5	0.828	1.16(0.60–2.24)	0.667
IV	48/41	9.5	70/58	13.3	0.076	0.68(0.45–1.03)	0.069
Surgery								0.953
No	71/55	11.7	100/73	13.4	0.117	0.67(0.44–0.99)	0.047
Yes	31/28	11.7	40/29	17.4	0.147	0.57(0.32–1.02)	0.058
Chemotherapy								0.551
No	34/26	10.0	25/18	11.3	0.401	0.57(.28–1.15)	0.117
Yes	68/57	12.0	115/84	16.9	0.090	0.69(0.48–0.98)	0.039
Radiotherapy								0.347
No	57/43	11.7	75/55	12.9	0.495	0.81(0.52–1.26)	0.349
Yes	45/40	11.7	65/47	17.4	0.026	0.50(0.32–0.80)	0.003

Note: n_p/n_d, number of all patients/number of death patients; SCC, Squamous cell carcinoma.

^*Data were calculated by Cox regression analysis, adjusted for age, smoking status, histology, TNM stage, surgery, chemotherapy, and radiotherapy status. The GG genotype was used as the reference group.