Figure 5. Identification of Compound 1 and its inhibition of STAT3- and STAT5b-SH2 binding.
(A) Chemical structure of Compound 1. (B) Dose-dependent inhibition of Compound 1 in the single assay. (C) Dose-dependent inhibition of Compound 1 in the multiplexed assay. Each point represents the mean from three replicates, and the error bars represent the standard deviation from the mean.