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. 2013 Aug 16;8(8):e71093. doi: 10.1371/journal.pone.0071093

Figure 3. iMDK induced growth inhibition in MDK-positive non-small cell lung carcinoma cells.

Figure 3

B. Growth inhibition by iMDK was increased in the MDK-positive HEK293, H441 and H520 cells but not the MDK-negative A549 cells or normal NHLF cells after 48 hours of treatment. Cell viability was assessed by trypan blue exclusion assay as described in Methods. Statistical significance was defined as p<0.01 (*). Dose-dependent growth inhibition by iMDK was observed morphologically in H441 lung adenocarcinoma cells. Shown are phase-contrast photomicrographs of H441 cells 48 hours after iMDK treatment (scale bar shows 100 μm).