Average increase in metabolic activity of fibroblast cells for cells exposed to ultrasound with respect to cells that were not exposed to ultrasound (incubator control/sham). The groups are separated into the three intensity levels (50 100, and 200 mW/cm2 SPTP), and within each level, the dark gray bar represents the 1 Hz PRF, the medium gray represents 10 Hz PRF, and the light gray represents 20 Hz PRF. Bars indicate standard error with six repetitions of each condition. *p < 0.05.