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. Author manuscript; available in PMC: 2014 Aug 15.
Published in final edited form as: Clin Cancer Res. 2013 Jun 18;19(16):4315–4325. doi: 10.1158/1078-0432.CCR-12-3937

Figure 4.

Figure 4

Challenges in the translation at bedside of a validated molecular classifier. Described are the steps taken by the modern oncologist when obtaining a prediction of a validated classifier for a single patient. Passing through these steps, particular problems and their potential solutions are highlighted in red boxes. To embrace precision medicine, the modern oncologist needs to develop or access competencies in molecular biology and in computational biology, in addition to clinical oncology.