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. 2013 May 1;19(1):195–202. doi: 10.2119/molmed.2013.00037

Figure 3.

Figure 3

HBSP suppresses the formation of atherosclerotic lesions within coronary artery segments of WHHLMI rabbits. (A) HBSP reduces mean cross-sectional arterial stenosis. Left circumflex arteries were collected from WHHLMI rabbits (control, n = 7; HBSP, n = 8) and were sectioned at 500-μm intervals. The percent cross-sectional stenosis was calculated as described in Materials and Methods. The mean number of arterial segments obtained was 20.7 ± 1.4 in control animals and 16.5 ± 0.9 in animals treated with HBSP. Data are mean ± SEM; *P < 0.01. (B) HBSP reduces atheromata (that is, those causing >75% significant stenosis of the vessel lumen). On the basis of the data obtained from (A), percentage of intima with significant atheromata was calculated. Data are mean ± SEM; *P < 0.01.