. Author manuscript; available in PMC: 2013 Dec 1.

Published in final edited form as: Pediatr Infect Dis J. 2012 Dec;31(12):1279–1283. doi: 10.1097/INF.0b013e31826fd3e7

Table 2.

Logistic regression analysis for the primary outcome of increase in CD4 count by at least 50 cells/mm³

Variables	Univariate						Multivariate
	24 Wks		48 Wks		End		24 Wks^a		48 Wks^a		End^b
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	Adj OR (95% CI)	P	Adj OR (95% CI)	P	Adj OR (95% CI)	P
Optimal regimen	0.97 (0.32-2.94)	0.96	3.17 (0.99-10.1)	0.051	3.26 (1.02-10.4)	0.046	0.92 (0.24-3.48)	0.90	4.40 (1.03-18.8)	0.046	5.39 (1.06-27.2)	0.042
Suboptimal regimen	ref		ref		ref		ref		ref		ref
Adherent	1.00 (0.36-2.77)	0.99	0.67 (0.24-1.86)	0.44	1.36 (0.48-3.81)	0.57	1.09 (0.31-3.81)	0.89	0.83 (0.23-2.99)	0.78	2.87 (0.70-11.8)	0.14
Non-adherent	ref		ref		ref		ref		ref		ref
Viral load < baseline	6.46 (1.84-22.7)	0.004	3.51 (1.03-11.9)	.044	2.37 (0.75-7.50)	0.14	8.01 (2.04-31.5)	0.003	3.04 (0.77-12.1)	0.11	3.04 (0.70-13.1)	0.14
Viral load ≥ baseline	ref		ref		ref		ref		ref		ref

Multivariable regression model included age at start of study regimen, baseline CD4 count, optimal vs. suboptimal regimen, adherent vs. nonadherent to the regimen, and viral load change

Multivariable regression model included age at start of study regimen, duration of regimen, baseline CD4 count, optimal vs. suboptimal regimen, adherent vs. nonadherent to the regimen, and viral load change

Adj OR = adjusted odds ratio, ARV = antiretroviral, CI = confidence interval, end = end of study period, P = p-value, OR = odds ratio, ref = reference, wks = weeks

Note: variables not presented were not significant in the model. Bolded values represent significant findings.