Table 2.

Univariable Analyses of Patient Factors Associated With Embryo Grade.^a

Risk factors	Grade I embryos	Grade II/III embryos	P valueb
ATRA, pmol/mL	7.0 (4.4-9.7) 29c	4.2 (2.6-5.8) 37	.06
Age, years	35.9 (33.9-37.8) 23d	33.9 (32.1-35.7) 27e	.14
BMI, kg/m2	28.5 (25.9-31.1) 23	24.8 (22.4-27.3) 27	.05
Day 3, FSH, IU/L	8.6 (6.9-10.2) 22	8.7 (7.2-10.2) 25	.90
Peak E2, pg/mL	1958 (1520-2396) 23	1934 (1530-2338) 27	.94
Total gonadotropins, pmol/mL	3538 (2745-4331) 23	3327 (2595-4059) 27	.70
Antral follicle count (AFC)	19.0 (12.1-25.8) 23	24.7 (18.4-31.0) 27	.22

Abbreviations: ATRA, all-trans retinoic acid; FSH, follicle-stimulating hormone.

^a A total of 50 women and 66 follicles were evaluated, 23 women (29 follicles) with grade I and 27 women (37 follicles) with grade II and/or III.

^b Grade I versus grade II/III.

^c Mean (95% confidence interval) number of follicles. Means are model-based means (not raw means) obtained from a repeated measures analysis of ATRA concentration from each ovary. The model-based means are the estimated means taking into consideration the fact that not all women have ATRA measurements from both ovaries.

^d Mean (95% confidence interval) number of women with at least 1 grade I embryo from the 2 follicles studied.

^e Mean (95% confidence interval) number of women with at least 1 grade II/III embryo (but no grade I embryo) from the 2 follicles studied.