Table 2.
Human genomic regions with synteny to the detected chromosome 1, 2, and 7 mouse QTLs for brain Aβ level, listed with previous reports in human linkage mapping or linkage disequilibrium studies of AD.
Chr | Human synteny | AD linkage/LD reports |
---|---|---|
1 | 1q43-44 | 1q44: Zubenko et al (1998) |
2 | 9q33 | 9q31: Myers et al (2002), 9q34: Pericak-Vance et al (2000) |
2q22-24 | 2q22, 2q24: Lee et al (2004) | |
7 | 11p14-15 | none |
15q12-13 | none |