Table 5.
Clinicopathologic discrepancies among subjects with PSG-confirmed or probable RBD who underwent autopsy.
| Clinical diagnosis | Neuropathologic diagnosis | All cases n = 22 | PSG-confirmed n = 7 | pRBD – +DEB n = 8 | pRBD – MSQ+ n = 7 |
|---|---|---|---|---|---|
| AD | LBD ± AD | 8 | 2 | 2 | 4 |
| CBS | LBD + AD | 2 | 1 | 0 | 1 |
| CBS | AD | 1 | 1 | 0 | 0 |
| FTD | AD | 1 | 0 | 1 | 0 |
| PD | MSA | 2 | 2 | 0 | 0 |
| PDD | AD | 2 | 0 | 0 | 2 |
| MSA | PSP | 1 | 1 | 0 | 0 |
| DLB | AD | 1 | 0 | 1 | 0 |
| DLB | CJD + ALS | 1 | 0 | 1 | 0 |
| DLB | Indeterminant | 1 | 0 | 1 | 0 |
| DLB | PSP + AD | 1 | 0 | 1 | 0 |
| Bins/AD | Bins/AD/LBD | 1 | 0 | 1 | 0 |
Abbreviations: AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; Bins, Binswanger disease; CBS, corticobasal syndrome; DLB, dementia with Lewy bodies; FTD, frontotemporal dementia; LBD, Lewy body disease; MSA, multiple system atrophy; PD, Parkinson’s disease; PDD, Parkinson’s disease with dementia; PSG, polysomnogram; PSP, progressive supranuclear palsy.