Figure 6. Colon colonization by enteric progenitors is enhanced by Raldh mutations.

a) Representative images from WT, R1^WTR2^HetR3^WT, R1^KOR2^HetR3^WT, R1^KOR2^HetR3^Het, and R1^KOR2^HetR3^KO mice show enteric neuron precursor cells (TuJ1⁺ cells, green) that colonized distal colon at E13.5. Scale bar: 500 μm. b) Quantification of extent of colon colonization by enteric progenitors (TuJ1⁺ cells, green) (*, p<0.05). Number of animals analyzed is indicated on each bar. All pairwise comparisons were done and all unlabeled comparisons were not significant (p>0.05).