Table 5.
Antibacterial activity of ligands and their organosilicon(IV) complexes.
| Compounds | Inhibition zone (mm) and activity index (AI)a | |||||
|---|---|---|---|---|---|---|
| Bacillus cereus | Nocardia spp. | Staphylococcus spp. | E. coli | Klebsiella spp. | E. aerogenes | |
| 100 μg/mL | 100 μg/mL | 100 μg/mL | 100 μg/mL | 100 μg/mL | 100 μg/mL | |
| L1H | 5.6 (0.394) | 5.9 (0.450) | 6.7 (0.453) | Inact. | Inact. | Inact. |
| Me3SiL1 | 7.8 (0.549) | 8.4 (0.641) | 8.2 (0.554) | 3.6 (0.283) | 2.8 (0.250) | 3.5 (0.280) |
| L2H | 6.6 (0.465) | 7.2 (0.550) | 7.9 (0.534) | Inact. | Inact. | Inact. |
| Me3SiL2 | 10.5 (0.739) | 11.9 (0.908) | 9.8 (0.662) | 3.9 (0.307) | 3.2 (0.286) | 3.5 (0.280) |
| L3H | 9.6 (0.394) | 9.9 (0.556) | 9.4 (0.635) | 6.7 (0.528) | 5.4 (0.482) | 6.2 (0.496) |
| Me3SiL3 | 12.6 (0.887) | 12.7 (0.969) | 12.9 (0.871) | 9.5 (0.748) | 9.9 (0.884) | 8.7 (0.696) |
| L4H | 8.5 (0.599) | 8.1 (0.618) | 8.7 (0.587) | 6.2 (0.488) | 7.4 (0.661) | 7.1 (0.568) |
| Me3SiL4 | 10.6 (0.745) | 12.4 (0.947) | 12.1 (0.818) | 9.8 (0.772) | 9.5 (0.848) | 10.8 (0.864) |
| Streptomycin | 14.2 | 13.1 | 14.8 | 12.7 | 11.2 | 12.5 |
a(AI): inhibition zone of test compounds/inhibition zone of standard.