Figure 4.

Cancer-targeted gene transfection by DNA/GRP78P-PATK polyplexes in PC3 cells. The results are normalized to the relative eGFP expression and cellular uptake by DNA/PATK polyplexes. Conjugation of cancer cell-targeting GRP78-binding peptide (GRP78P) significantly enhanced the transfection and cellular uptake of DNA/PATK polyplexes. ** indicates p < 0.01.