Table 2.

Summary of KIT exon 9, 11, 13 and 17 mutations detected in adenoid cystic carcinoma of the salivary gland and comparison with KIT mutations in gastrointestinal stromal tumors reported in major studies

Case	Exon	Substitution	Type	Mutation	KIT mutations reported in gastrointestinal stromal tumors
3	Exon 11	1673C>T	Missense	Pro551Leu	Pro551Leu Met552del	Antonescu et al17
3	Exon 11	1747C>T	Missense	Leu576Phe	Leu576Phe	Zamo et al20, Gomes et al21
3	Exon 11	1755T>C	Silent	Tyr578
3	Exon 11	1759C>T	Missense	His580Tyr
5	Exon 17	2458C>T	Silent	Leu813
7a	Exon 11	1693A>G	Missense	Lys558Glu	Lys558Ile Val559del	Zamo et al20
Lys558Gln	Antonescu et al17
7a	Exon 11	1706A>T	Missense	Glu562Val
7a	Exon 11	1792T>C	Missense	Phe591Leu
7a	Exon 17	2459T>C	Missense	Leu813Pro
7b	Exon 9	1508A>T	Missense	Asp496Val
7b	Exon 9	1476C>T	Silent	His485
7b	Exon 17	2430T>C	Silent	Gly803
8	Exon 9	1470C>T	Silent	Phe483
8	Exon 11	1731C>T	Silent	Tyr570
8	Exon 13	1936T>C	Missense	Ser639Pro
8	Exon 17	2415C>T	Silent	Ile798
10	Exon 9	1512G>A	Silent	Val497
10	Exon 9	1555A>G	Missense	Asn512Asp
10	Exon 11	1771T>C	Missense	Phe584Leu
11	Exon 13	1949T>C	Missense	Val643Ala	Val643Ala	Lasota et al23
12	Exon 17	2486A>G	Missense	Asn822Ser	Asn822Lys, Asn822His Asn822Tyr	Lasota et al23