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Effect of linopirdine and chromanol on SMC outward current. (A) Currents were evoked by stepping to +40 mV and were reduced by linopirdine (Lino; 30 μM). (B) Outward currents were reduced by chromanol 293B (Chr; 30 μM). (C, D) Summary bar charts of the significant reduction of SMC outward current by linopirdine (n = 5) and chromanol 293B (n = 7). *P < 0.05, significantly different from control.
