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. 2013 Mar 26;22(6):649–657. doi: 10.1002/pds.3430

Table 2.

Characteristics of the two nested case–control populations

Mortality Reinfarction


Cases Controls Cases Controls




N % N % N % N %
841 3329 778 3083
Fatal 387 49.7
Nonfatal 391 50.3
Exposure
 No EB therapy 221 26.3 501 15.0 191 24.6 426 13.8
 1 EB drug 199 23.7 677 20.3 173 22.2 536 17.4
 2 EB drugs 224 26.6 999 30.0 209 26.9 926 30.0
 3 EB drugs 176 20.9 968 29.1 176 22.6 951 30.8
 Complete EB therapy 21 2.5 184 5.5 29 3.7 245 7.9
Interventions during index admission
 PCI 236 28.1 1429 42.9 284 36.5 1482 48.0
 Bypass 10 1.2 76 2.3 6 0.8 75 2.4
Comorbidities (index admissions and 9 years before)
 Malignant neoplasm 210 25.0 428 12.9 96 12.3 309 10.0
 Diabetes 262 31.2 546 16.4 248 31.9 488 15.8
 Disorders of lipid metabolism/obesity 85 10.1 377 11.3 141 18.1 362 11.7
 Hematologic diseases 171 20.3 327 9.8 113 14.5 265 8.6
 Hypertension 445 52.9 1349 40.5 404 51.9 1119 36.3
 Conduction disorders 123 14.6 380 11.4 92 11.8 338 11.0
 Cardiac dysrhythmias 334 39.7 931 28.0 263 33.8 749 24.3
 Heart failure 391 46.5 786 23.6 279 35.9 590 19.1
 Other cardiac diseases 257 30.6 663 19.9 199 25.6 501 16.3
 Cerebrovascular disease 262 31.2 663 19.9 186 23.9 522 16.9
 Diseases of arteries,
 Arterioles and capillaries 448 53.3 1083 32.5 389 50.0 830 26.9
 Chronic obstructive
 Pulmonary disease 176 20.9 463 13.9 146 18.8 334 10.8
 Chronic nephropathies 214 25.4 384 11.5 180 23.1 308 10.0
 Chronic liver, pancreas,
 Digestive diseases 54 6.4 124 3.7 46 5.9 126 4.1
 Gastro-oesophageal
 haemorrhage 39 4.6 77 2.3 28 3.6 53 1.7
EB drug use 12 months before admission (2+ prescriptions)
 Antiplatelet 326 38.8 1048 31.5 269 34.6 802 26.0
 Beta blockers 106 12.6 410 12.3 97 12.5 334 10.8
 ACE-inhibitors/Sartans 464 55.2 1727 51.9 374 48.1 1412 45.8
 Statins 120 14.3 382 11.5 126 16.2 350 11.4

EB, evidence based.