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. Author manuscript; available in PMC: 2013 Aug 19.
Published in final edited form as: Eur J Epidemiol. 2012 Sep 19;27(9):673–687. doi: 10.1007/s10654-012-9730-6

Table 3.

Comparison of P-values for each variable, obtained from the applied regression methods on CAC in AGES-Reykjavik 2002-2006 (n = 5,213). Models fitted for each variable separately by sex, adjusting for age and excluding people with history of coronary events

Males
Females
Modelled as: ZINB-
logistic
part
ZINB-
count part
Linear
regression
ln(CAC+1)
Linear
regression
Box-Coxc
Quantile
regression
ZINB-
logistic
part
ZINB-
count part
Linear
regression
ln(CAC+1)
Linear
regression
Box-Coxc
Quantile
regression
Physical and physiological
BMI Continuous * *** *** *** ***
Systolic blood pressure (10 mmHg) Continuous * ** ** *** *** ***
Pulse pressure (10 mmHg) Continuous * *** ** *** *** ***
Total serum cholesterol (mmol/L) Continuous * **
HDL cholesterol (mmol/L) Continuous ** *** *** *** ***
Triglycerides (mmol/L) Continuous ** ** *** *** ***
C-reactive protein (mg/L) Continuous * ** ** ** *** *** ***
Diabetes mellitus, type II (No is reference) Categorical ** a * a ** a ** a *** a
 Newly diagnosed *
 Previously known diabetes ** * ** * ** ** ***
Smoking Never (reference) Categorical ** a *** a *** a *** a *** a *** a *** a *** a
 Former ** * *** *** *** ** *** *** ***
 Current ** ** *** *** *** *** ***
Cardiovascular profile
Family history of myocardial infarction Categorical ** ** *** *** *** *** *** *** ***
Chest pain from heart disease Categorical * ** **
Mini stroke or TIA Categorical * * *
Carotid intima thickness (mm) Continuous *** *** *** *** *** *** *** *** ***
Plaque, moderate or more in carotid artery Categorical *** *** *** *** *** *** *** *** *** ***
Medications
Analgesics Categorical * ** *** *** *** * *** *** *** ***
Anticoagulants Categorical *** *** *** *** * ** *** *** ***
Aspirin Categorical *** *** *** *** * ** *** *** ***
Statins Categorical *** *** *** *** *** ** *** *** ***
Medication for hypertension Categorical ** *** *** *** *** ** *** *** *** ***

Total number of associations b 7 12 (13) 12 13 13 16 15 (17) 18 17 18
*

P-value <0.05

**

P-value <0.01

***

P-value <0.001

Abbreviations: BMI, Body mass index; CAC, Coronary artery calcium; HDL, High density lipoprotein; TIA , Transient ischemic attack; ZINB, Zero inflated negative binomial

a

P-value from Wald-test, Ho: all coefficients=0

b

Total number of associations from the ZINB-model shown in parenthesis.

c

Power transformation 0.20 (95% CI 0.19, 0.21)

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