TABLE 1.

Number of animals (eyes) examined in the various models

	Route of administration	Intravitreous *		Systemic †
Model	Total animals	Flatmount	Cryosection	Flatmount	Cryosection
OIR	8	8 (16)	ND	ND	ND
I/R‡	20§	6 (6)	4 (4)	6 (12)	4 (8)
STZ-induced diabetic mice	12§	4 (4)	2 (2)	4 (8)	2 (4)
Normal control mice	12§	4 (4)	2 (2)	4 (8)	2 (4)
BBZDR/Wor diabetic rats	12§	12 (12)	ND	ND	ND
BBZDR/Wor control rats	12§	12 (12)	ND	ND	ND

^*One eye from each animal received cells by intravitreous injection.

^†Both eyes from each animal were included for analysis.

^‡One eye from each animal was injured and given cells by intravitreous injection; the contralateral eye was used as unaffected control.

^§Animals were divided equally to receive huEPCs of either nondiabetic or diabetic origin. ND, not done.