FIG. 3.

Amelioration of alterations in monoaminergic neurotransmitters with aging on long-term bacosides treatment. Concentration of serotonin, norepinephrin, and dopamine (ng/gram wet tissue) in the cortex of young, middle-aged, and aged treated or untreated rats. Values are expressed as mean±standard deviation of 6 animals in each group. Level of significance as calculated by one-way analysis of variance (ANOVA) followed by post hoc least significant difference: (*) p<0.05 for young versus aged; (†) p<0.05 for young versus middle-aged treated; and (#) p<0.05 for aged untreated versus aged treated group. 5-HT, 5-hydroxytryptamine; NE, norepinephrine; DA, dopamine. (Reprinted, with permission, from Rastogi et al.⁷)