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. Author manuscript; available in PMC: 2013 Aug 19.
Published in final edited form as: Nature. 2009 Dec 17;462(7275):868–874. doi: 10.1038/nature08625

Figure 1. An example of parental origin determination.

Figure 1

In blue and red are two phased haplotypes of a proband. Among other typed individuals, the closest paternal relative known to also carry the blue haplotype is R1, a cousin, while the corresponding maternal relative is R2. For the red haplotype, a maternal aunt (R3) carries the haplotype, while the closest known carrier on the father side is R4. Since R1 is a closer than R2 and R3 is a closer than R4, the blue and red haplotypes are likely paternally and maternally inherited respectively. The single-tile score (see Methods) supporting this assignment is 0.194.